Nano technology

Drug delivery system

Overview of recently developed nanoformulations for lipophilic nutraceuticals

Nanoemulsion

Capsaicin o/w nanoemulsions with enhanced skin permeation were successfully prepared by controlling the ratios of the surfactant mixtures, oleoresin capsicum as the oil phase, and aqueous phase.


The selected nanoemulsions showed great potential as transdermal delivery carriers for enhancing the permeation of core materials

Nanoliposome

Chitosan-coated curcumin nanoliposomes (CS-Cur-NLs) were fabricated by the ethanol injection method (EIM).


EIM-generated CS-Cur-NLs showed higher bioavailability, with enhanced high mucoadhesive property, storage stability, and encapsulation efficiency.


Publication


  • Solid lipid nanoparticles loaded thermoresponsive pluronic–xanthan gum hydrogel as a transdermal delivery system. J APPL POLYM SCI. 46004 (2018)

  • Soluble starch formulated nanocomposite increases water solubility and stability of curcumin. FOOD HYDROCOLLOID. 56, 41-49 (2016)

  • Effects of chitosan coating on curcumin loaded nano-emulsion: Study on stability and in vitro digestibility. FOOD HYDROCOLLOID (60, 138, 2016)

  • Recent developments in nanoformulations of lipophilic functional foods. TRENDS FOOD SCI TECH. 46, 144-157 (2015)

  • Preparation of a Capsaicin-Loaded Nanoemulsion for Improving Skin Penetration. Journal of agricultural and food chemistry. 725-732 (2014)

  • Spatial–temporal event adaptive characteristics of nanocarrier drug delivery in cancer therapy. J CONTROLLED RELEASE. 172, 281–291. (2013)

  • Preparation of Chitosan-Coated Nanoliposomes for Improving the Mucoadhesive Property of Curcumin Using the Ethanol Injection Method. Journal of agricultural and food chemistry. 11119-11126 (2013)